Sample Reconstructed Data of CheckMate214 Study
cm214_pfs.Rd
The progression-free survival data reconstructed from the publication of the CheckMate214 study.
Usage
data(cm214_pfs)
Format
A dataset containing 3 columns:
- time
the time-to-event variable (the time unit is month)
- status
the event indicator (1=event, 0=censor)
- arm
the treatment indicator (1=treatment, 0=control)
Source
Motzer RJ, Tannir NM, McDermott DF, et al. Nivolumab plus ipilimumab versus sunitinib in advanced renal-cell carcinoma. New England Journal of Medicine. 2018;378(14):1277-1290. <doi:10.1056/NEJMoa1712126> Guyot P, Ades AE, Ouwens MJ, Welton NJ. Enhanced secondary analysis of survival data: reconstructing the data from published Kaplan-Meier survival curves. BMC Med Res Methodol. 2012;12(1):9. <doi:10.1186/1471-2288-12-9>
Details
This is a reconstructed patient-level data from the results reported by Motzer et al.(2018) <doi:10.1056/NEJMoa1712126>. The data consists of 847 patients with previously untreated clear-cell advanced renal-cell carcinoma; 425 for the nivolumab plus ipilimumab group (treatment) and 422 for the sunitinib group (control).